The San Donato Research Hospital (Policlinico San Donato) is the largest and most renowned Italian center specialized in the field of cardiovascular treatments. Founded in 1969 the multi-specialty healthcare institution is a leader in Italy and among best centers in Europe as for the amount as well as for the complexity of performed cardiac surgery and interventional cardiology procedures in children (over 1,000 procedures per year) and adult patients (over 1,000 surgical interventions and 6,000 interventional cardiology procedures). The San Donato’s Arrhythmology and Electrophysiology Unit delivers one of the highest numbers of cardiac ablations in the world (over 1,400 per year). San Donato has a research center aimed at studying of the heart and blood vessels in adults and children and searching of new prevention and treatment methods that has been recognized by the Italian Ministry of Health as a Scientific Institute for Research, Hospitalization and Health Care (IRCCS). Since 2019, Policlinico San Donato has become home to the National Institute for Obesity Cure (INCO), a national reference center with a multidisciplinary approach for the diagnosis and treatment of obesity. Thanks to the INCO, dietary, psycho-behavioral and surgical treatments are carried out together with the most innovative video-assisted laparoscopic and mini-invasive techniques.